Asymmetric synthesis is the hot point of organic synthesis in recent years. Asymmetric catalytic method is one of the most prospective methods to obtain pure chiral compounds.
不对称合成是当代有机合成的热点，不对称催化方法是获取单一异构手性化合物最具有前景的方法之一。
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The catalyzed asymmetric synthesis was the effective method to prepare the optics active compounds, the pentamethide obtaines the widespread application as the reagent or the catalyst in this domain.
Combining the advantages of biocatalysis in nonaqueous media, asymmetric reduction of corresponding carbonyl compounds using microbial cells is an efficient method to produce these chiral alcohols.