An interactive digital experience with impartial advice, targeting teenagers. Cocaine Basement is a realistic portrayal of the physical and psychological damage caused by cocaine abuse.

The phrase "substance abuse" is often used instead of "drug abuse" to make clear that substances such as alcohol and tobacco can be just as harmfully misused as heroin and cocaine.

Changes in synaptic plasticity in dopamine neurons of the ventral tegmental area (VTA) may contribute to circuit modification induced by many drugs of abuse, including cocaine.