The most common neural tube defects are spina bifida, in which the spin al cord fails to close completely during fetal development, and anencephaly, in which part or all of the brain doesn't develop.

Daily supplementation with folic acid for 1 month prior to conception and during pregnancy may reduce the incidence of neural tube defects such as spina bifida and anencephaly in the child.

Results There are 96 neural malformation with more common hydrocephalus anencephaly exencephaly and spina bifida in all malformations of 359 cases accounting for 26.7%.