OBJECTIVE: To explore the expressions of MMP and collagen in cartilage tissues in knee articularcartilages defects and surface defects models.
目的：观察膝关节骨软骨缺损及表面软骨缺损动物模型关节软骨组织中胶原及基质金属蛋白酶的表达变化。
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Methods: Chondrocytes were isolated from articularcartilages of 3 week old rabbits and formed cartilages by cultivation in centrifuge tubes for 2 weeks.