A handful of genes that are normally active in the developing embryo are expressed in a differentiated cell, such as a skin cell, causing that cell to revert back to its undifferentiated state.
一些通常在发育胚胎中活跃的基因会被分化细胞(比如皮肤细胞)表达,促使细胞回复到未分化状态。
2
Nasopharyngeal cancers were primarily undifferentiated carcinomas (89%), whereas nonnasopharyngeal upper respiratory tract carcinomas were predominantly squamous cell (88%).
鼻咽癌是主要的未分化癌(89%),然而非鼻咽部上呼吸道癌主要是鳞状细胞癌(88%)。
3
This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state.