But no variant of prion protein was able to prevent demyelination when introduced specifically into the Schwanncells that surround and support peripheral nerve cells.
但当向神经末梢周围的雪旺细胞注入这种蛋白时,没有变异的蛋白能阻止退化。
2
Aguzzi theorizes that PrP is a signaling molecule in axons that's needed to "keep Schwanncells happy."
Aguzzi推理说,PrP就是轴突里的信号分子,会使施沃恩细胞健康快乐。
3
Even though the Schwanncells are the ones affected when PrP is missing, the protein must be present in axons to prevent disease, the researchers report online this week in Nature Neuroscience.