The replication of parvovirus is strongly dependent on cellular factors associated with proliferation and differentiation, especially those related to the S-phase of the cellcycle.
细小病毒的复制紧紧依赖于和增殖及分化有关的细胞因子,尤其是和细胞周期S-期有关的因子。
2
Conclusion HCMV induces elevated levels of P53, which may affect its normal function in regulating checkpoints of cellcycle, and facilitate its own replication in host cell.
The inhibitive effect of prodigiosin on multiplication of cancer cells was related to the inhibiting of DNA replication in S stage and regulating of cellcycle.