Loss of neurofibromin expression in NF1-associated tumors is associated with elevated RAS activity and increased cellproliferation.
在与 NF1 相关的肿瘤中神经纤维蛋白表达的丧失与 RAS 活性升高和细胞增殖增加有关。
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Such models offer exciting new insights into cellproliferation, differentiation and immune function, and are providing a platform to understand normal tissue homeostasis and transition to disease.