Then it was observed whether the inactived genes in leukemia cell lines were actived after the treatment with 5-aza-deoxycytosin, a kind ofdemethylation agent .
应用5-杂氮脱氧胞嘧啶处理上述白血病细胞系，观察去甲基化处理对失活基因的影响；
2
The invention relates to compounds of a general formula (1) and pharmaceutically acceptable salts, and mainly discloses 4'-substituted 13-cyclo-aza-lactone derivatives.
Methods The survival rate and apoptosis rate of QBC939 after being treated with different density of 5-aza-2'-deoxycytidine were detected by using the method of MTT and flow cytometry.