The abnormality of neurofilaments(NF) plays a possible role in axonaldegeneration of Alzheimer's Disease(AD), but the mechanism remains unclarified.
阿尔茨海默病（AD）患者脑中神经细丝异常可能在其轴突退化中起重要作用，但机制不明。
2
Conclusion: Local high concentration of DMSO can delay axonaldegeneration, which indicates that DMSO can be used for adjuvant treatment of neurodegenerative diseases.
结论：局部高浓度的DMSO能够延缓轴突的退行性病变，提示DMSO可能用于神经退行性疾病的辅助治疗。
3
The above changes in disconnected group were similar to those in positive control group. No obvious protective effects on axonaldegeneration were observed in blank and DMSO control groups.