Objective to explore the SV40-mediated immortalization, the related factors and their roles in cellimmortalization.
目的探讨SV40如何介导细胞永生化，与细胞永生化现象相关的因素及它们的作用。
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Telomere and telomerase are the focus of modern biological study. There are close relationships among telomere loss and cell ageing, activation of telomerase, cell senescence and immortalization.