ATM kinase regulates a number of proteins involved in cellcyclecheckpoint control, apoptosis, and DNA repair.
AT M激酶调节许多蛋白,涉及细胞周期检验点的控制、细胞凋亡和DNA修复。
2
To maintain genomic integrity, cells have evolved complex surveillance mechanisms termed cellcyclecheckpoint.
为确保遗传准确性,细胞形成了复杂的细胞周期监督机制,即细胞周期检验点。
3
Several factors, such as defects in chromosome segregation and DNA damage response, failure of cellcyclecheckpoint, telomere dysfunction, may cause chromosomal instability.