One of the early success stories of computational systems biology was the work done on cell-cycle regulation.
计算系统生物学的一个早期的成功故事是在细胞周期调控上所做的工作。
2
In normal cells, p21 ACTS like a brake to block cellcycle progression in the event of DNA damage, preventing the cells from dividing and potentially becoming cancerous.
在正常的细胞中，如果DNA受损，p 21就会像刹车一样阻断细胞周期进程以防止细胞分裂和癌变。
3
They found that the famous tumor suppressor gene, p53, arrested the cellcycle when DADS treatment was present.