Conclusion Chronicfluorosis has no obvious effect on myocardial collagen metabolism of rats and myocardial collagen is not likely the main target of fluoride.
结论：慢性氟中毒对大鼠心肌胶原代谢无明显影响，心肌胶原可能不是氟化物作用的靶子。
2
Chronic fluorine exposure may cause abnormal calcium accumulation in bone structure (fluorosis) due to low-level systemic absorption.
慢性氟暴露会导致由于低水平的系统吸收引起的在骨骼结构里的异常钙积累(氟中毒)。
3
Objective To investigate the expression of BMP-2 in mice incisor enamel organ cells under chronic fluoride exposure and elucidate the mechanism of dental fluorosis.