AIM: To explore the effects of carbenoxolone (CBX), a gap junction blocker, on the neuron injury induced by focal cerebral infarct.
目的：探讨缝隙连接阻断剂甘珀酸对大鼠光化学局灶性脑梗死神经元损害的影响。
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Methods: Experimental rats were intrathecally injected with carbenoxolone(CBX), a special gap junction blocker, and the control rats with the saline.
方法：向实验组大鼠鞘内注射一种缝隙连接的阻断剂甘珀酸；
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CONCLUSION: the seizure can be enhanced by CBX pretreatment and it may relate with astrocytic hyperplasia and the increasing expression of Cx43 in astrocytes.