Objective: to establish an efficient method to detect fragile X chromosomesyndrome (FraX) by optimizing PCR amplifying condition.
目的:优化PCR扩增条件,建立一种有效检测脆性X综合征的方法。
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Prior studies have indicated that babies born to older women have higher risks of birth defects, low birth weight and certain chromosome problems, such as Down syndrome.
Fragile X syndrome, a single genetic mutation on the X chromosome, is the most common source of inherited mental impairment, affecting one in every 4,000 boys and one in every 6,000 girls.