Rearrangement — Chromosome breakage followed by reconstitution in an abnormal combination. If unbalanced, the rearrangement can produce an abnormal phenotype.
染色体结构改变造成遗传物质的重新排列。若为非平衡型重排,则可导致异常表型。
2
Otherwise, the chromosome break and rearrangement induced by radiation maybe play important pole in leading to the translocation and misalignment of cancer genes and other correlated genes.
另外,辐射所致染色体的断裂和重排对癌基因和其他相关基因的移位和失调可能起着重要作用。
3
The difference of karyotype may be caused by different sample treatments or allogenic polymorphism of chromosome karyotype due to chromosomal configuration rearrangement and regional diversities.