Trapped Neutrophil Syndrome is an autosomalrecessivedisease which results in mature neutrophils being unable to migrate from the bone marrow into the blood.
Mutations in the corresponding ATM gene result in ataxia telangiectasia (at), an autosomalrecessivedisease characterized by uncoordinated muscle movement and neurodegeneration.
AT M基因突变可导致共济失调毛细血管扩张症(AT),一种常染色体隐性遗传病,该病特点是不协调的肌肉运动和神经退化。