The medial group mainly distribute in the rostal part of the internal capsule and basal nucleus; the lateral group mainly distribute in the caudal part.

Most of these shortcuts involve limbic structures at the sub-cortical level, including the basal ganglia, hippocampus, thalamus and nucleus accumbens.

The basal membrane of fusiform fibroblasts with oval nucleus and rich in chromatin reached much protuberance into matrix of HA ECM and collagen fibril cumulating outside cells.