Cellulose binding domains improve the binding and facilitate the activity of catalyticdomains on the insoluble substrate, but not on soluble substrate.
纤维素吸附区促进酶与底物的结合，有利于催化区对不溶性底物的作用，但对可溶性底物的催化作用无影响。
2
The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalyticdomains.