Appearance of withdrawal reactions may associated with pharmacological effects on serotonin, dopamine, norepinephrine, GABA and cholinergictransmitter in central nervous system.
Considered as a transmitter and medium of non-cholinergic and non-adrenergic nerves, no involves in introduction of sense of pain and transmission of aesthesis.
NO被认为是非胆碱能、非肾上腺素能神经的递质或介质，参与痛觉传入与感觉传递过程。
3
It has been proved the nervous system which transmitter is NO widely distributes in human body and is as important as adrenergic and cholinergic nerves and neuropeptides.