AIM: To construct phage human antiidiotypic antibody library.
目的：构建噬菌体人源抗独特型抗体库。
2
But at present, many antiidiotypic antibodies are mouse original antibodies, which can cause human anti mouse antibody (HAMA) response and decrease the curative effect.
但由于目前所使用的抗独特型抗体多为鼠源性，用于人体可产生人抗鼠抗体反应，从而影响疗效。
3
Objective:To investigate the induction effect of anti-idiotypic antibodies on mice specific low immune reactive state.