The mechanism of multidrug resistance is vary, while much attention was paid on the expression of ABC(ATPbindingcassette) transporter.
肿瘤多药耐药的机制十分广泛,其中以ATP结合盒式结构超家族成员研究较多。
2
ABCG2 is a half ATP-bindingcassette (ABC) transporter that facilitates efflux of a wide variety of substrates ranging from natural products to synthetic anticancer drugs.
A BCG2是半ATP结合盒转运体。它可以转运内源性物质和人工合成的抗肿瘤药物等多种底物。
3
Objective To investigate whether ATP-bindingcassette transporter 1 (ABCA1) R219K genetic variation is correlated with blood lipids.