But at present, many antiidiotypicantibodies are mouse original antibodies, which can cause human anti mouse antibody (HAMA) response and decrease the curative effect.
但由于目前所使用的抗独特型抗体多为鼠源性，用于人体可产生人抗鼠抗体反应，从而影响疗效。
2
Objective:To investigate the induction effect of anti-idiotypicantibodies on mice specific low immune reactive state.
目的：探讨抗独特型抗体对小鼠特异性低免疫反应状态的诱导作用。
3
The experiments also demonstrated that 15 of 24 other monoclonal anti-DNA antibodies represented idiotypic cross-reactivity with H241 in different degrees.