Conclusions anti VEGF may provide a new approach to the treatment of gastric cancer by inhibiting tumor angiogenesis, and combination of anti VEGF antibody with MMC could be more effective.

Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor-associated angiogenesis and have become the new targets of anti-tumor therapy.

Vascular endothelial growth factor (VEGF) and its receptor play a critical role in tumor associated angiogenesis and has become the new targets of anti tumor therapy.