Gene targeting technology and its application in research of animalmodel of human disease were briefed in this paper.
本文就基因打靶技术及其在人类疾病动物模型研究中的应用做一介绍。
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CONCLUSION:This animalmodel reflects the physiopathological changes of menopause depression disease in the aspects of productive endocrine hormone and neurotransmitter.
结论：该动物模型生殖内分泌激素与神经递质两方面均较好地反映了更年期抑郁症的病理生理变化。
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Conclusion trisomy 16 mice occur with congenital megacolon, and trisomy 16 mice may be also regard as an animalmodel for Hirschsprung's disease.