Objective: To observe the expression of poly (ADP-ribose) polymerase (PARP) in focal cerebral ischemia with reperfusion injury and explore the role of PARP in apoptosis.
The cleavage of Poly(ADPribose)polymerase(PARP) is an molecular event of the activation of cysteine protease, and it is also an early molecular marker of apoptosis .
的蛋白酶解为半胱氨酸蛋白酶激活的分子事件，是细胞程序死亡的一个早期分子标志。
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Inhibition of poly (ADP-ribose) polymerase has preventive and therapeutic effects on the treatment of shock and ischemia-reperfusion injury.