DNA binding domains that are elongated, with a shape that is somewhat like a finger. The shape of the domain is coordinated by one or more zinc atoms.
伸展的、形状有些像手指的DNA结合域。这一形状由一个或多个锌原子进行协调。
2
Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-bindingdomain to the DNA cleavage domain of a restriction enzyme.
锌指核酸酶是一种人工制做限制性内切酶,通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。
3
The functional expression of DNA bindingdomain of Zif268 will greatly facilitate the development of in vivo genetic selection assay for the study of Zinc fingers-DNA interaction.