肌肉的分化与膜的电压-门控离子通道(voltage-gated ion channels)的表达是依赖于促细胞分裂剂的消退和细胞的生长停滞。通常,电压-门控通道能诱发肌细胞的特异基因产物,但其致癌性的基本机理仍不明...
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?电压门控通道
...,离子通道作为重要的靶点仍然是药物研发中迅速增长的热点,配体门控(ligand-gated)和电压门控通道(voltage-gated ion channels)在现有药物作用的前五位的基因靶点中分别排在第三和第四位,仅排在G蛋白偶联受体(GPCR) 和核受体家族(nuclear receptor)之后,分...
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?电压门控性离子通道
voltage-gated ion channels电压门控性离子通道 calcium dependent neutral protease 钙离子激活的中性蛋白酶 ..
Because the binding of the neurotransmitter (ligand) to the receptor activates these ionchannels, they are called ligand-gated channels to distinguish them from voltage-gated channels.