Conclusion The analgesic effect of IS was presumably caused by modulation of voltage-gated sodium channels in primary sensory neurons besides structure destruction of myelin sheath and axon membrane.
Furthermore, the external calcium was found to influx mainly through N-type calcium channels and voltage-gated sodium channels.
我们进一步用膜通道阻断剂验证,发现胞外钙的流入主要是通过N型钙通道和电压门控钠通道流入胞内的。
3
Using cell-attached and inside-out configuration of patch damp, we record a type of voltage-gated potassium channels in the cell membrane of cultured star-shape neurons of the new born rat cortex.