Phyllodestumor shows a wide spectrum of morphology. There are no clearly distinct boundaries between PT and fibroadenoma.
叶状肿瘤形态谱系宽泛，与纤维腺瘤之间没有明确的界限。
2
Copy number analysis revealed intratumoral heterogeneity and evidence for divergent tumor evolution in malignant phyllodes tumors with and without heterologous differentiation.
拷贝数分析显示肿瘤具有异质性，具有异源性分化的恶性叶状肿瘤有不同的肿瘤演化。
3
The results identify novel pathways involved in the pathogenesis of malignant phyllodes tumors, which significantly increase our understanding of tumor biology and have potential clinical impact.