Conclusion 5f inhibits tubulinpolymerization and depolymerization, and leads to cell cycle arrested, and possibly induces apoptosis.
结论5f能抑制体外微管蛋白聚合,从而可能是影响细胞的细胞周期及诱导凋亡途径之一。
2
Results 5f decreased the Absorption values of the reaction system. and markedly inhibited not only tubulinpolymerization but also tubulin depolymerization.
结果5f能抑制反应体系吸光值升高,提示它对微管蛋白聚合具有抑制作用并能抑制其解聚。
3
The result suggested that TBZ may induce aneuploidy by the pathway of tubulinpolymerization inhibition which is able to lead to chromosomal malsegregation.