Due to overlapping specificities of the transport proteins, drug interactions at the level of tubularsecretion is an event that may occur in clinical situation.
Renal clearance is used to determine renal elimination mechanisms of a drug, which is the result of glomerular filtration, active tubularsecretion and reabsorption.
肾清除率常用来表示药物在肾中的排除机制，它是肾小球滤过和肾小管分泌与重吸收的作用结果。
3
The physiological function of kidney includes glomerular filtration, tubular resorption and secretion as well as its endocrine functions.