Context: Sodium-glucose cotransporter 2 (SGLT2) expressed in the proximal renal tubules accounts for about 90% of the reabsorption of glucose from tubular fluid.
背景:钠-葡萄糖协同转运蛋白2(SGLT2)在近端肾小管表达,负责重吸收肾小管液中90%的葡萄糖。
2
It directly increases proximal tubular sodium reabsorption.
它能直接升高近端小管对钠的重吸收。
3
Renal clearance is used to determine renal elimination mechanisms of a drug, which is the result of glomerular filtration, active tubular secretion and reabsorption.