Objective: to establish an efficient method to detect fragile X chromosome syndrome (FraX) by optimizing PCR amplifying condition.
目的:优化PCR扩增条件,建立一种有效检测脆性X综合征的方法。
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Method: the diagnosis was made according to clinical manifestation, cytology, bacteriology, ot, chest X-ray film, bronchoscopy, lung ct, MRI, sputum tuberculin PCR and the other related examinations.
The PCR-Sequence gel silver staining was more rapid, immediate, simple and economy, which suits to the colony screening fragile X syndrome on a large scale.