Female mosaicism of the X chromosome has major implications for human health and disease and is the leading cause of female protection from X-linkedgenetic disorders.
女性作为X染色体的杂合子在人类的健康与疾病中及重要作用,并可避免X连锁遗产性疾病在女性中发生。
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Objective to identify the disease locus in X - linked retinitis pigmentosa (XLRP) families using genetic linkage analysis.