Es is caused by long-standing left-to-right shunt lesions, which induce pulmonary vascular changes, resulting in reversal of the shunt flow.
ES是由长期左向右分流引起，该左向右分流诱导了肺血管改变，导致分流方向逆转即右向左分流。
2
Objective To establish a rat model of pulmonary hypertension induced by left-to-right shunt and explore the influence of high pulmonary blood flow on pulmonary vascular collagen remodeling.
目的建立左向右分流所致肺动脉高压大鼠模型，了解高肺血流量对肺血管胶原代谢的影响。
3
These serve to shunt blood from the arterial to the venous side of the vascular system, thereby avoiding the capillaries, where exchange of oxygen and heat takes place.