Objective: To determine the rate of prenatal detection of ultrasonography abnormalities in fetuses with trisomy18 and evaluate its predictive value.
目的:探讨孕期18 -三体胎儿超声异常的产前检出率及临床价值。
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CONCLUSIONS: The extent to which free fetal DNA testing can be applied as a universal screening tool for trisomy 21, 18, and 13 depends mainly on assay accuracy and cost.