The recombinant strain also had lower adhesiveness(P>0.05)and significantly lower relative invasiveness to the HeLa cells than its wildtypestrain(P<0.05).
Pakistan is affected by nationwide transmission of WPV1, and is the location of the only wild poliovirus type 3 (WPV3) case in Asia in 2011 (a strain on the verge of elimination on the continent).
Besides, the strain is wildtype with very clear genetic background, which is fit for genetic improvement and is hopeful to improve the capability of disposing the organic waste gas greatly.