Female wild-type mice on an ethanol-rich diet had 4 times as much alanine aminotransferase (ALT), indicating liver injury, than mice lacking the osteopontin gene.
雌性野生种小鼠的丙氨酸转氨酶是基因敲除鼠的4倍,这提示肝损伤的存在;
2
In current, different kinds of methods were widely used in the animal model, such as the wildtype, congenital defect and gene modification.
目前野生型、先天缺陷型、基因修饰等动物模型被广泛应用在这一研究领域。
3
But wildtype GFP and EGFP are not ideal to detect the transient changes of gene expression regulation.