Most recently, or more recently, there was a vaccine for varicella, which was developed in the last ten years.

An important safety issue related to the varicella vaccine is the impact on the epidemiology of herpes zoster both in vaccinees as well as in individuals previously infected with wild-type varicella.

With regard to varicella vaccine, the reluctance to vaccination were due mostly to the avoidance of medical interventions and perceived unseriousness of varicella.