The recent data indicating that some TRIM proteins are implicated in ubiquitination, as a novel class of RING finger ubiquitin E3 ligases.
最近的一些研究显示TRIM家族可能是一类新的RING指泛素连接酶。
2
Research studies suggest that activated E2 associates transiently with E3, and the dissociation is a critical step for ubiquitination (4).
研究表明,激活的E2与E3迅速结合然后分离是一个关键步骤(4)。
3
Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26s proteasome.