Continuous delivery of rotigotine as transdermal patches could offer similar efficacy to oral pramipexole in patients with fluctuating Parkinson's disease over 6 months of treatment.

Objective To prepare anemonin patches with higher transdermal flux in order to provide proof for the development of anemonin transdermal preparation.

Aim: To study the in vitro transdermal diffusion behavior of self-prepared tretionin patches.