Hypoxia inducible factor-l (HIF-1), which can stimulate expression of hypoxia induced-responsed, is a kind of transcriptive factor.
缺氧诱导因子- 1 (H IF - 1)是由低氧等诱导细胞产生的1种转录因子，能激活许多缺氧反应性基因的表达。
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Conclusion Chronic intermittent hypoxia can increase rat liver microsomal ERD and ANH activities. The mechanism is related to up-regulation of CYP3A2 and CYP2E1 expression at the transcriptive levels.