The family of ErbB tyrosinekinasereceptors can transmit signals derived from growth factor of epidermal growth factor family.
属于酪氨酸激酶受体,可以传递表皮生长因子家族的信号。
2
Sorafenib is an oral multikinase inhibitor with activity against tyrosinekinasereceptors that are responsible for blood vessel development and has shown to be active in treating advanced RCC.
索拉非尼是口服的多激酶抑制剂,可以抑制酪氨酸激酶受体,后者促进血管生成并在肾细胞癌中显示出高活性。
3
I suspect the way this worked when the first transmembrane receptorstyrosinekinase evolved was simply to make activation contingent on phosphorylation of one receptor by the other.