In the course of leucocytopenia, lymphocyte increased relatively whereas the change of integral value of neutrophil's toxic granule was not vary markedly.

The character of granule, cultivation of special granule and its application to COD removal, de-nitrogen, toxic chemicals degradation, heavy metal adsorption in wastewater treatment were reviewed.

Conclusion Huangzi Zhike granule has a certain therapeutic effect for acute bronchitis with the syndrome of wind-cold attacking the lung, and has no toxic and side effects.