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1 ?硫鸟嘌呤 ...性的研究-中国学术期刊网络出版总库 S-腺苷-L-甲硫氨酸(S-adenosyl-L-methionine,SAM)作为甲基供给体,6-硫鸟嘌呤(6-thioguanine,6-TG)作为酶反应底物,TPMT催化6-TG生成2-氨基-6-甲基巯基嘌呤(2-amino-6-methyl... 2 ?硫乌嘌呤 ... 优福定(UFT) 硫乌嘌呤(Thioguanine) 丝裂霉素(Mitomycin C) ... 3 ?巯鸟嘌呤 急性早幼粒细胞白血病的治疗 固治疗,DFS为86;而西班牙PETHEMA试验采用二者联合Ara-C、VP-16或Ara-C 6-巯鸟嘌呤(6-thioguanine, 6-TG)巩固,DFS为90,显示DFS及OS与蒽环类药物是否联合Ara-C无差异,PETHEMA的最新研究显 4 ?鸟嘌呤 ...性的研究-中国学术期刊网络出版总库 S-腺苷-L-甲硫氨酸(S-adenosyl-L-methionine,SAM)作为甲基供给体,6-硫鸟嘌呤(6-thioguanine,6-TG)作为酶反应底物,TPMT催化6-TG生成2-氨基-6-甲基巯基嘌呤(2-amino-6-methyl...
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The entropy effect on the Gibbs free energy of 7-thioguanine base is very small and there is little significance for the tautomeric equilibria of the base. 硫代鸟嘌呤互变异构的熵效应小,对互变异构平衡没有显著的影响,而焓变对互变异构产生了主要的影响。 - 2
Mercaptopurine has been a standard component of long-term continuing treatment for childhood lymphoblastic leukaemia, whereas 6-thioguanine has been mainly used for intensification courses. 背景6 -巯基嘌呤是治疗儿童淋巴细胞白血病的一种标准的长期维持用药,而6 -硫鸟嘌呤则主要用于强化治疗。
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