The pathogenesis of IBS is complicated, current pathophysiologic theories are based on abnormalities of brain-gutaxis.
IBS的病因和发病机理复杂，目前主要以脑-肠轴异常理论为基础。
2
So we presume that the attribution to the spleen meridian is correlated with the regulation of brain-gutaxis, and the compatibilities influence herbs' selective effects on brain-gutaxis.
即归脾经可能与脑-肠轴调控作用有关，且复方配伍影响药物对脑-肠轴的选择性作用。
3
In summary, a variety of different mechanisms in braingutaxis, alone or in combination, may be responsible for visceral hypersensitivity.