DNA strand scission and topology changes are catalyzed by DNA topoisomerases.
DNA拓扑异构酶与断开dna链和改变其拓扑结构有关。
2
The specific inhibitors of DNA topoisomerases are the useful tool in studying their biological functions.
寻找及发现其抑制剂是研究它的生物学功能的重要途径。
3
Another example is that of researchers at GlaxoSmithKline who recently described a novel class of antibacterial agents that target type IIA topoisomerases.