A total of 358 patients with severe aorticstenosis, a heart disease characterized by obstruction of the aorticvalve due to calcification, participated in the trial.
总计358名伴严重主动脉瓣狭窄(特征为因钙化主动脉瓣梗阻的一种心脏病)患者参加了这项实验。
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BACKGROUND: -transcatheter aorticvalve implantation is an alternative to open heart surgery in patients with aorticstenosis.
背景：除了心内直视手术，经导管主动脉瓣植入术是主动脉狭窄患者的替代治疗方案。
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Jana Pausa, 76, of Atherton, Calif., who had both severe aorticstenosis and lung disease that made her unsuitable for open-heart surgery to replace the diseased heart valve, is one such patient.
Jana Pausa, 76岁，加利福尼亚州阿瑟顿人，有严重主动脉瓣狭窄和使她不适合开心手术置换病损心脏瓣膜的肺部疾病，是一个这样的病例。